For relief of these disorders ...

It is a structural analog of carnitine, its maximum concentration in plasma is reached within 2-3 hours. Produced the drug in capsules of 0.25 g or 5 ml ampoules of 10% solution. Mildronate possesses anticonvulsant and stimulant effect. Parenteral its use since the early days of abstinence syndrome (3-4 injections of 5 ml of 10% solution / day) prevents the development of patients with seizures that characterize barbiturate withdrawal syndrome, and nausea are characteristic for these forms of drug addiction severe asthenic disorders (feeling of weakness, fatigue, lethargy etc.). Length of treatment averages 5-7 days. Side effects and complications when applying mildronate not observed. Optimal regimens of withdrawal in addiction caused by receiving stimulant, is a combination of drugs affecting dopaminergic mechanisms (bromocriptine), docked in the first place asthenic syndrome and partly neurological disorders, and resources that affect the serotonergic system (fluvoxamine), a pronounced impact on affective component of the syndrome. Bromocriptine (Parlodel) is administered to patients in the early days of the withdrawal syndrome in a daily dose of 2,5-3,75 mg. After the relief of acute abstinence phenomena of treatment with extended doses of 1,0-1,25 mg orally per day for several months to prevent a possible update to the drug craving and relapse prevention. Fluvoxamine (floksiral) - an antidepressant with a predominantly serotoninergic components of the action, shall be appointed when there are major signs of withdrawal symptoms: depressed mood, apathy, lethargy, weakness, irritability. Average daily dose is 150 mg 3 times. Duration of therapy - from one week to two months. Symptomatic treatment parallel to that described pathogenetic drug therapy and symptomatic treatment detoxification activities with drugs commonly used for this purpose, including vitamins. The structure of withdrawal symptoms in patients addicted to a large extent presented psychopathological disorders, mainly in the form of affective and symptomatology. For relief of these disorders is recommended to use antipsychotics and antidepressants. Doses are selected individually. When choosing an antidepressant preference should be given drugs with, along with timoanalepticheskim, sedative or balanced action. Of the antidepressants amitriptyline is recommended - the average daily dose of 75-100 mg, gerfonal (100-150 mg), anafranil (75-100 mg), pirazidol (150-200 mg), ludiomil (75-100 mg), fluvoxamine (150-200 mg), azafen (100-125 mg), or miansan lerivon (30-60 mg). With more severe depression amitriptyline administered parenterally, approximately 2.0 ml of 1% solution 2-3 times a day. Since depressive disorders with the syndrome of deprivation often accompanied by dysphoria, anxiety, restlessness, antidepressants are best combined with soft neuroleptics.