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Treatment is carried out in stages The first stage involves detoxification activities and relief of withdrawal symptoms with normalization somatonevrologicheskih violations and correction of psychopathic disorder. Further therapy is aimed at the complete elimination of metabolic disorders, behavioral disorders, and normalization of mental status (including sleep). The third stage is to identify the main sindromokompleksa psychic dependence (psychopathological clearance craving for drugs, particularly its dynamics - a periodic or permanent presence in patients with signs of attraction) and the appointment of targeted treatment. The last step is to identify the conditions preceding the recurrence of the disease and sindromokompleksa psychic dependence on this phase of the disease to the appointment of anti-maintenance treatment. It focuses on the reasons causing the aggravation of craving for drugs, a situation leading to the actualization of this symptom, as well as the identification of endogenous factors that contribute to spontaneous mainstream attraction. The first two phases of treatment is most advisable to carry out in a hospital, the third and fourth - an outpatient basis. Pathogenetic therapy proved that chronic intoxication with narcotic drugs cause an imbalance in certain systems neyromediatsii. Therapy aimed at addressing this imbalance contributes to relief of the main clinical syndromes of drug addiction. Therefore, the choice of therapeutic interventions appropriate to dwell on the pathogenetic therapeutic agent in combination with traditional methods of detoxification and psychotropic drugs. Application of modern tools and techniques relieve withdrawal symptoms provides for an immediate total denial of drug use, except in cases of abuse of barbiturates and other sedatives or other drugs in combination with high doses of sleeping pills-sedatives. The most effective means of arresting the pathogenetic opium withdrawal symptoms are clonidine (clonidine) - agonist, alpha-2-adrenergic receptors of the CNS, tiaprid (tiapridal) - an atypical neuroleptic from the group of substituted benzaminov, Tramal (tramadol hydrochloride) - a central analgesic action. Complex use of these drugs - the best way to arrest the main manifestations of abstinence syndrome. Clonidine therapy begins with the first day of abstinence, and continued for 5-9 days, gradually reducing the dose. The initial daily dosage of the drug should not exceed 0,6-0,9 mg per os for 3-4 receptions. Clonidine fastest fully suppresses somatovegetative disorder; to a much lesser extent, it affects psychopathology and algicheskuyu symptoms. Among the side effects the drug may include dry mouth, severe sedation, lowering blood pressure. In the case of a fall in blood pressure below 90/60 mm Hg.